Complete genetic characterization of a Brazilian dengue virus type 3 strain isolated from a fatal outcome.

نویسندگان

  • Marize Pereira Miagostovich
  • Flávia Barreto dos Santos
  • Túlio Machado Fumian
  • Flávia Ramos Guimarães
  • Eliane Veiga da Costa
  • Fernando Neto Tavares
  • Janice Oliveira Coelho
  • Rita Maria Ribeiro Nogueira
چکیده

We have determined the complete nucleotide and the deduced amino acid sequences of Brazilian dengue virus type 3 (DENV-3) from a dengue case with fatal outcome, which occurred during an epidemic in the state of Rio de Janeiro, Brazil, in 2002. This constitutes the first complete genetic characterization of a Brazilian DENV-3 strain since its introduction into the country in 2001. DENV-3 was responsible for the most severe dengue epidemic in the state, based on the highest number of reported cases and on the severity of clinical manifestations and deaths reported.

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عنوان ژورنال:
  • Memorias do Instituto Oswaldo Cruz

دوره 101 3  شماره 

صفحات  -

تاریخ انتشار 2006